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Writer's pictureDR ZARYAB

All you need to know about depression


Depression is often mistaken for simple sadness, but it is a complex mental health condition that can profoundly impact your life. While sadness is a temporary emotional response to specific events, depression is characterized by persistent feelings that interfere with daily functioning. Here’s an in-depth look at depression, including its types, symptoms, causes, diagnosis, prognosis, and treatment.


What is Depression?


Depression is a serious mental health disorder marked by persistent feelings of sadness, hopelessness, and a loss of interest in activities once enjoyed. Unlike temporary sadness, which typically resolves on its own, depression requires intervention by a professional to manage effectively. It is just like any other medical illness like heart attack, diabetes, hypertension etc. It affects how you feel, think, and handle daily activities, potentially leading to severe emotional and physical issues.




Types of Depression


  1. Major Depressive Disorder (MDD):


    • Description: Characterized by intense and persistent symptoms that interfere with daily life.

    • Symptoms: Severe mood swings, inability to perform everyday tasks, significant changes in weight and sleep patterns, and thoughts of death or suicide.


  2. Seasonal Affective Disorder (SAD):

    • Description: Occurs at specific times of the year, usually during the fall and winter months.

    • Symptoms: Similar to MDD, including low energy, irritability, changes in sleep and appetite, but these symptoms typically resolve with the onset of spring and summer.


  3. Peripartum Depression:

    • Description: Also known as postpartum depression, this type occurs during pregnancy or within the first year after childbirth.

    • Symptoms: Extreme sadness, anxiety, and exhaustion that can make it difficult for new mothers to care for themselves or their baby.


  4. Dysthymia (Persistent Depressive Disorder):

    • Description: A chronic form of depression where symptoms are less severe but last for a longer duration, typically for at least two years.

    • Symptoms: Persistent low mood, low self-esteem, and reduced interest in daily activities.


  5. Psychotic depression

    Persistent low mood is accompanied by hallucinations and delusions



Signs and Symptoms


Signs and Symptoms of Major Depressive Episode



1. A depressed mood and a loss of interest or pleasure

2. Feeling blue, hopeless, in the dumps, or worthless

3. Trouble sleeping, especially early morning awakening or hypersomnia

4. Decreased appetite and weight loss, or increased appetite and weight gain

5. Inability to concentrate and impairments in thinking

6. Depressed mood most of the day, and nearly every day

7. Psychomotor agitation or retardation

8. Fatigue and decreased energy

9. Feeling worthless with guilt

10. Suicidal and recurrent morbid thoughts







Causes of Depression

Depression arises from a combination of genetic, biological, environmental, and psychological factors:


  • Genetic Factors: Family history of depression increases the risk, suggesting a genetic predisposition.


  • Biological Factors: Imbalances in brain chemicals (neurotransmitters) like serotonin,dopamine, glutamate and norepinephrine are linked to depression.


  • Environmental Factors: Trauma, abuse, significant life changes, or prolonged stress can trigger depressive episodes.


  • Psychological Factors: Low self-esteem, excessive self-criticism,poor and unhealthy thinking styles or unresolved trauma can contribute.


  • Medical Conditions: Chronic illnesses such as diabetes or hormonal imbalances can also play a role.


  • Substance Abuse: Alcohol or drug misuse can exacerbate or lead to depressive symptoms.


How is Depression Diagnosed?


Diagnosing depression involves several steps:


  1. Clinical Interview: A detailed discussion with a healthcare professional about symptoms, their impact on life, and the duration of these symptoms.


  2. Medical History: A review of past mental health issues, family history of depression, and any current medications or health conditions.


  3. Psychological Assessment: Utilization of standardized questionnaires like the PHQ-9 or Beck Depression Inventory to evaluate the severity and impact of symptoms.




Prognosis


The outlook for individuals with depression varies but is generally positive with appropriate treatment. 80% people experience significant improvement with proper treatment and can manage their symptoms effectively.Whereas unfortunately 20-25 % of patients experience treatment resistance and then are referred for more complex interventions. Early intervention and a comprehensive treatment plan often lead to a better prognosis in most cases.



Treatment Options



Effective treatment for depression typically involves a combination of approaches:


  1. Medication:


    • Antidepressants: Medications such as SSRIs (Selective Serotonin Reuptake Inhibitors) and SNRIs (Serotonin-Norepinephrine Reuptake Inhibitors), MAOIs,TRICYCLICS and other atypical antidepressants can help balance brain chemicals and improve mood.


  2. Psychotherapy:


    • Cognitive-Behavioral Therapy (CBT): Helps individuals identify and change negative thought patterns and behaviors.

    • Interpersonal Therapy (IPT): Focuses on improving personal relationships and social skills.

    • Psychodynamic Therapy: Explores unconscious thoughts and feelings that influence behavior.

    • Mindfulness based cognitive behavioral therapy

      Combines the effects of cbt with element of mindfulness.Mostly used for relapse prevention



  3. Lifestyle Changes:

    • Exercise: Regular physical activity can boost mood and energy levels.

    • Healthy Diet: Nutrient-rich foods support overall well-being.

    • Sleep: Establishing a consistent sleep routine improves mood and energy.

    • Natural supplements research shows natural supplements such as saffron,fish oil, zinc etc are of help in depression



  4. Support:

    • Support Groups: Connecting with others facing similar challenges can provide emotional support and practical advice.

    • Social Support: Engaging with friends and family for encouragement and understanding.


Conclusion


Understanding depression is crucial for managing and overcoming the condition. Recognizing the signs and seeking professional help are key steps toward recovery. With the right treatment and support, many people with depression lead fulfilling and productive lives. If you or someone you know is experiencing symptoms of depression, reaching out to a mental health professional can make a significant difference.



REFERENCES TAKEN FROM: KAPLAN AND SADOCKS TEXTBOOK OF PSYCHIATRY


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